1446511-14-3

1446511-14-3 structure

Name: Fmoc-L-Lys(4-N3-Z)-OH
Chemical Name: Fmoc-L-Lys(4-N3-Z)-OH
CAS Number: 1446511-14-3
Molecular Formula: C₂₉H₂₉N₅O₆
Molecular Weight: 543.57
Catalog: Research Areas Others
Create Date: 2022-11-21 07:33:46
Modify Date: 2025-09-21 09:06:37
Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys(4-N3-Z)-OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition[1][2].

Name	Fmoc-L-Lys(4-N3-Z)-OH

Description	Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys(4-N3-Z)-OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Ge Y, et al. A genetically encoded multifunctional unnatural amino acid for versatile protein manipulations in living cells. Chem Sci. 2016 Dec 1;7(12):7055-7060. [2]. Wesalo JS, et al. Phosphine-Activated Lysine Analogues for Fast Chemical Control of Protein Subcellular Localization and Protein SUMOylation. Chembiochem. 2020 Jan 15;21(1-2):141-148.

Molecular Formula	C₂₉H₂₉N₅O₆
Molecular Weight	543.57