2692623-26-8

2692623-26-8 structure

Name: C12 NBD Globotriaosylceramide
Chemical Name: C12 NBD Globotriaosylceramide
CAS Number: 2692623-26-8
Molecular Formula: C₅₄H₉₁N₅O₂₁
Molecular Weight: 1146.32
Catalog: Research Areas Others
Create Date: 2022-10-11 14:25:38
Modify Date: 2024-01-22 21:16:09
C12 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide has been used to detect ceramide trihexoside[1].

Name	C12 NBD Globotriaosylceramide

Description	C12 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide has been used to detect ceramide trihexoside[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	C12 NBD globotriaosylceramide accumulates in human umbilical vascular endothelial cells (HUVECs) treated with the α-galactosidase A inhibitor in a concentration-dependent manner[2].
References	[1]. Kassiani Kytidou, et al. Nicotiana benthamiana α-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease. J Biol Chem. 2018 Jun 29;293(26):10042-10058. [2]. Janet Hsu, et al. Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease. J Control Release. 2011 Feb 10;149(3):323-31.

Molecular Formula	C₅₄H₉₁N₅O₂₁
Molecular Weight	1146.32