2761321-26-8

2761321-26-8 structure
2761321-26-8 structure
  • Name: BRD4-BD1-IN-2
  • Chemical Name: BRD4-BD1-IN-2
  • CAS Number: 2761321-26-8
  • Molecular Formula: C20H15Br3N4O2
  • Molecular Weight: 583.07
  • Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
  • Create Date: 2022-11-19 16:13:19
  • Modify Date: 2024-04-02 19:45:02
  • BRD4-BD1-IN-2 is a selective BRD4-BD1 inhibitor, with an IC50 of 2.51 µM (20-times greater than that of BD2). BRD4-BD1-IN-2 can be used in studies of cancer and cardiovascular diseases[1].

Name BRD4-BD1-IN-2
Description BRD4-BD1-IN-2 is a selective BRD4-BD1 inhibitor, with an IC50 of 2.51 µM (20-times greater than that of BD2). BRD4-BD1-IN-2 can be used in studies of cancer and cardiovascular diseases[1].
Related Catalog
Target

BRD4-BD1:2.51 μM (IC50)

BRD4-BD2:>50 μM (IC50)

References

[1]. Chang Y, et al. Design, synthesis, biological evaluation, and molecular docking of 1, 7-dibenzyl-substituted theophylline derivatives as novel BRD4-BD1-selective inhibitors. Medicinal Chemistry Research, 2021, 30(8): 1453-1468.

Molecular Formula C20H15Br3N4O2
Molecular Weight 583.07