1132758-87-2
1132758-87-2 structure
- Name: Blosozumab
- Chemical Name: Blosozumab
- CAS Number: 1132758-87-2
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Others
- Create Date: 2022-10-24 08:00:16
- Modify Date: 2026-03-25 20:04:02
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Blosozumab (LY2541546) is an anti-Human sclerostin (SOST) antibody inhibitor. Blosozumab stimulates bone formation and reduces bone resorption. Blosozumab can be used in the research of Osteoporosis[1][2].
| Name | Blosozumab |
|---|
| Description | Blosozumab (LY2541546) is an anti-Human sclerostin (SOST) antibody inhibitor. Blosozumab stimulates bone formation and reduces bone resorption. Blosozumab can be used in the research of Osteoporosis[1][2]. |
|---|---|
| Related Catalog | |
| Target |
sclerostin (SOST)[1] |
| In Vivo | Blosozumab (1-100 mg/kg, i.v.) shows effects of hyperostosis in rats[1]. Animal Model: Sprague-Dawley rats [2] Dosage: 1, 10, and 100 mg/kg Administration: Intravenous injection (i.v.), once every 3 days (5-week study) or once weekly (6-month study) Result: Observed the bone anabolic effects. Showed significant bleeding and morbidity at 100 mg/kg. Decreases in the numbers of platelets. Increased number of bone marrow megakaryocytes at 100 mg/kg. |
| References |
| No Any Chemical & Physical Properties |