384857-54-9

384857-54-9 structure

Name: Antitubercular agent-30
Chemical Name: N-(4-nitrophenyl)-2-thiophen-2-ylacetamide
CAS Number: 384857-54-9
Molecular Formula: C₁₂H₁₀N₂O₃S
Molecular Weight: 262.28
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2022-10-18 18:46:39
Modify Date: 2024-08-13 21:28:03
Antitubercular agent-30 is an antibacterial agent against Mycobacterium tuberculosis (MIC=50 μg/mL). Antitubercular agent-30 has little cytotoxic effect on murine macrophage cells (LD85=~100 μg/mL)[1].

Name	N-(4-nitrophenyl)-2-thiophen-2-ylacetamide

Description	Antitubercular agent-30 is an antibacterial agent against Mycobacterium tuberculosis (MIC=50 μg/mL). Antitubercular agent-30 has little cytotoxic effect on murine macrophage cells (LD85=~100 μg/mL)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Antitubercular agent-30 (compound 16) (0.1-100 μg/mL; 18 h) 的浓度低于 10 μg/mL 时，对小鼠巨噬细胞无细胞毒作用[1]。
References	[1]. Silva Lourenço MC, et al. Synthesis and biological evaluation of N-(aryl)-2-thiophen-2-ylacetamides series as a new class of antitubercular agents. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6895-8.