708992-34-1
708992-34-1 structure
- Name: SIRT5 inhibitor 4
- Chemical Name: SIRT5 inhibitor 4
- CAS Number: 708992-34-1
- Molecular Formula: C18H15N3O4S
- Molecular Weight: 369.39
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Sirtuin
- Create Date: 2022-09-01 09:43:14
- Modify Date: 2023-02-23 13:23:40
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SIRT5 inhibitor 4 (compound 11) is a potent, selective SIRT5 inhibitor with IC50 values of 26.4 and >400μM for SIRT5 and other SIRT subtype, respectively[1].
| Name | SIRT5 inhibitor 4 |
|---|
| Description | SIRT5 inhibitor 4 (compound 11) is a potent, selective SIRT5 inhibitor with IC50 values of 26.4 and >400μM for SIRT5 and other SIRT subtype, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
SIRT5:26.4 μM (IC50) SIRT1:＞400 μM (IC50) SIRT2:＞400 μM (IC50) SIRT3:＞400 μM (IC50) SIRT6:＞400 μM (IC50) SIRT7:＞400 μM (IC50) |
| In Vitro | SIRT5 inhibitor 4 (compound 11) (6-200 µM) stabilizes SIRT5 protein with a temperature shift of 1.8℃ in a dose-dependent manner[1]. |
| References |
| Molecular Formula | C18H15N3O4S |
|---|---|
| Molecular Weight | 369.39 |