1415456-99-3
1415456-99-3 structure
- Name: Cagrilintide
- Chemical Name: Cagrilintide
- CAS Number: 1415456-99-3
- Molecular Formula: C194H312N54O59S2
- Molecular Weight: 4409
- Catalog: Signaling Pathways GPCR/G Protein CGRP Receptor
- Create Date: 2022-08-31 23:22:54
- Modify Date: 2026-07-03 13:38:57
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Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity[1][2][3].
| Name | Cagrilintide |
|---|
| Description | Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity[1][2][3]. |
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| Related Catalog | |
| In Vivo | Cagrilintide (compound 23) (0.1, 1, 3, 10, 30 nmol/kg; s.c.) reduces food intake in the rat[2]. Cagrilintide (10 nmol/kg; i.v. or s.c.) shows good pharmacokinetic parameters[2]. Animal Model: 12 weeks, 400 g Sprague Dawley male rats[2] Dosage: 0.1, 1, 3, 10, 30 nmol/kg Administration: S.c.; once for 80 h Result: Reduced food intake in the rat for several days at doses in the range of 1-10 nmol/kg. Animal Model: 12 weeks, 400 g Sprague Dawley male rats[2] Dosage: 10 nmol/kg Administration: I.v.; s.c. Result: Showed good pharmacokinetic parameters with T1/2 of 20±2, 27±3 h for i.v. and s.c., respectively. |
| References |
| Molecular Formula | C194H312N54O59S2 |
|---|---|
| Molecular Weight | 4409 |
| Exact Mass | 4408.2582207 |