2332820-04-7

2332820-04-7 structure

Name: ACSS2-IN-2
Chemical Name: 2332820-04-7
CAS Number: 2332820-04-7
Molecular Formula: C₂₁H₁₉F₂N₃O₄
Molecular Weight: 415.4
Catalog: Research Areas Cancer
Create Date: 2022-09-25 17:47:04
Modify Date: 2025-09-18 17:58:32
ACSS2-IN-2 is an acyl-CoA synthetase short-chain family member 2 (ACSS2) inhibitor. ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer[1].

Name	2332820-04-7

Description	ACSS2-IN-2 is an acyl-CoA synthetase short-chain family member 2 (ACSS2) inhibitor. ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Research Areas >> Neurological Disease
Target	IC50: 3.8 nM (ACSS2)[1]
In Vitro	ACSS2-IN-2 (Compound 261) (5 h) has ACSS2 inhibitory activity with an IC50 value of 3.8 nM in MDA-MB-468 cells[1].
References	[1]. Philippe Nakache, et al. Acss2 inhibitors and methods of use thereof. Patent. WO2019097515A1.

Molecular Formula	C₂₁H₁₉F₂N₃O₄
Molecular Weight	415.4