2499713-65-2

2499713-65-2 structure
2499713-65-2 structure
  • Name: TbPTR1 inhibitor 1
  • Chemical Name: TbPTR1 inhibitor 1
  • CAS Number: 2499713-65-2
  • Molecular Formula: C22H21N7O
  • Molecular Weight: 399.45
  • Catalog: Research Areas Infection
  • Create Date: 2022-08-29 13:51:01
  • Modify Date: 2024-04-05 18:51:04
  • TbPTR1 inhibitor 1 (compound 5d) is a potent kinetoplastid pteridine reductase 1 (PTR1) inhibitor with an IC50<0.1 nM for TbPTR1. TbPTR1 inhibitor 1 has inhibitory activity against Trypanosoma brucei (EC50=0.66 μM)[1].

Name TbPTR1 inhibitor 1
Description TbPTR1 inhibitor 1 (compound 5d) is a potent kinetoplastid pteridine reductase 1 (PTR1) inhibitor with an IC50<0.1 nM for TbPTR1. TbPTR1 inhibitor 1 has inhibitory activity against Trypanosoma brucei (EC50=0.66 μM)[1].
Related Catalog
Target

IC50: <0.1 nM (TbPTR1)[1]

References

[1]. Pöhner I, et al. Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1. J Med Chem. 2022 Jun 8.

Molecular Formula C22H21N7O
Molecular Weight 399.45