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2499713-65-2

2499713-65-2 structure

2499713-65-2 structure

Name: TbPTR1 inhibitor 1
Chemical Name: TbPTR1 inhibitor 1
CAS Number: 2499713-65-2
Molecular Formula: C₂₂H₂₁N₇O
Molecular Weight: 399.45
Catalog: Research Areas Infection
Create Date: 2022-08-29 13:51:01
Modify Date: 2024-04-05 18:51:04
TbPTR1 inhibitor 1 (compound 5d) is a potent kinetoplastid pteridine reductase 1 (PTR1) inhibitor with an IC50<0.1 nM for TbPTR1. TbPTR1 inhibitor 1 has inhibitory activity against Trypanosoma brucei (EC50=0.66 μM)[1].

Name	TbPTR1 inhibitor 1

Description	TbPTR1 inhibitor 1 (compound 5d) is a potent kinetoplastid pteridine reductase 1 (PTR1) inhibitor with an IC50<0.1 nM for TbPTR1. TbPTR1 inhibitor 1 has inhibitory activity against Trypanosoma brucei (EC50=0.66 μM)[1].
Related Catalog	Research Areas >> Infection
Target	IC50: <0.1 nM (TbPTR1)[1]
References	[1]. Pöhner I, et al. Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1. J Med Chem. 2022 Jun 8.

Molecular Formula	C₂₂H₂₁N₇O
Molecular Weight	399.45

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