2415018-86-7

2415018-86-7 structure

Name: RSV-IN-5
Chemical Name: RSV-IN-5
CAS Number: 2415018-86-7
Molecular Formula: C₂₈H₃₇N₇O₂
Molecular Weight: 503.64
Catalog: Signaling Pathways Anti-infection RSV
Create Date: 2022-08-25 16:55:56
Modify Date: 2023-02-23 15:29:48
RSV-IN-5 (Compound 4) is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. RSV-IN-5 exhibits potent anti-RSV activities against not only wild-type A2 F protein (EC50=2.0 nM), but also D486N-mutant F protein (EC50=8.1 nM)[1].

Name	RSV-IN-5

Description	RSV-IN-5 (Compound 4) is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. RSV-IN-5 exhibits potent anti-RSV activities against not only wild-type A2 F protein (EC50=2.0 nM), but also D486N-mutant F protein (EC50=8.1 nM)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> RSV
References	[1]. Toru Yamaguchi-Sasaki, et al. Discovery of a potent dual inhibitor of wild-type and mutant respiratory syncytial virus fusion proteins through the modulation of atropisomer interconversion properties. Bioorg Med Chem. 2020 Dec 15;28(24):115818.

Molecular Formula	C₂₈H₃₇N₇O₂
Molecular Weight	503.64