2098181-84-9
2098181-84-9 structure
- Name: KRpep-2d
- Chemical Name: KRpep-2d
- CAS Number: 2098181-84-9
- Molecular Formula: C109H183N43O25S2
- Molecular Weight: 2560.02
- Catalog: Signaling Pathways GPCR/G Protein Ras
- Create Date: 2022-08-22 08:06:23
- Modify Date: 2024-01-20 11:09:24
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KRpep-2d is a potent K-Ras inhibitor and inhibits proliferation of K-Ras-driven cancer cells. KRpep-2d can be used for cancer research[1].
| Name | KRpep-2d |
|---|
| Description | KRpep-2d is a potent K-Ras inhibitor and inhibits proliferation of K-Ras-driven cancer cells. KRpep-2d can be used for cancer research[1]. |
|---|---|
| Related Catalog | |
| Target |
K-RAS |
| In Vitro | KRpep-2d has cyclic structure with importance for K-Ras inhibitory activity. Leu77 , Ile9 and Asp12 are critical amino acid residues for the K-Ras inhibitory activity of KRpep-2d[1]. KRpep-2d (10-30 μM) has inhibitory activity of A427 cells with the proliferation rates of 68.3% (10 μM) and 48.3% (10 μM)[1]. |
| References |
| Molecular Formula | C109H183N43O25S2 |
|---|---|
| Molecular Weight | 2560.02 |