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2417231-16-2

2417231-16-2 structure

2417231-16-2 structure

Name: FFA1 agonist-1
Chemical Name: FFA1 agonist-1
CAS Number: 2417231-16-2
Molecular Formula: C₂₇H₃₆ClNO₃
Molecular Weight: 458.03
Catalog: Signaling Pathways GPCR/G Protein GPR40
Create Date: 2022-08-05 13:38:17
Modify Date: 2025-08-25 13:14:23
FFA1 agonist-1 (Compound 17a) is an orally active fatty acid receptor 1 (FFA1) agonist with an EC50 of 0.75 μM. FFA1 agonist-1 can be used for type 2 diabetes mellitus research[1].

Name	FFA1 agonist-1

Description	FFA1 agonist-1 (Compound 17a) is an orally active fatty acid receptor 1 (FFA1) agonist with an EC50 of 0.75 μM. FFA1 agonist-1 can be used for type 2 diabetes mellitus research[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GPR40 Research Areas >> Metabolic Disease
Target	EC50: 0.75 μM (FFA1)[1]
In Vivo	FFA1 agonist-1 (Compound 17a) (0-25 mg/kg; p.o.) reduces the plasma glucose levels in a dose-dependent manner in mice[1].
References	[1]. Kuranov SO, et al. Exploring bulky natural and natural-like periphery in the design of p-(benzyloxy)phenylpropionic acid agonists of free fatty acid receptor 1 (GPR40). Bioorg Chem. 2020 Jun;99:103830.

Molecular Formula	C₂₇H₃₆ClNO₃
Molecular Weight	458.03

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