2417231-16-2

2417231-16-2 structure
2417231-16-2 structure
  • Name: FFA1 agonist-1
  • Chemical Name: FFA1 agonist-1
  • CAS Number: 2417231-16-2
  • Molecular Formula: C27H36ClNO3
  • Molecular Weight: 458.03
  • Catalog: Signaling Pathways GPCR/G Protein GPR40
  • Create Date: 2022-08-05 13:38:17
  • Modify Date: 2024-01-04 20:14:38
  • FFA1 agonist-1 (Compound 17a) is an orally active fatty acid receptor 1 (FFA1) agonist with an EC50 of 0.75 μM. FFA1 agonist-1 can be used for type 2 diabetes mellitus research[1].

Name FFA1 agonist-1
Description FFA1 agonist-1 (Compound 17a) is an orally active fatty acid receptor 1 (FFA1) agonist with an EC50 of 0.75 μM. FFA1 agonist-1 can be used for type 2 diabetes mellitus research[1].
Related Catalog
Target

EC50: 0.75 μM (FFA1)[1]

In Vivo FFA1 agonist-1 (Compound 17a) (0-25 mg/kg; p.o.) reduces the plasma glucose levels in a dose-dependent manner in mice[1].
References

[1]. Kuranov SO, et al. Exploring bulky natural and natural-like periphery in the design of p-(benzyloxy)phenylpropionic acid agonists of free fatty acid receptor 1 (GPR40). Bioorg Chem. 2020 Jun;99:103830.

Molecular Formula C27H36ClNO3
Molecular Weight 458.03