422276-47-9

422276-47-9 structure
422276-47-9 structure
  • Name: EGFR/HER2/CDK9-IN-3
  • Chemical Name: EGFR/HER2/CDK9-IN-3
  • CAS Number: 422276-47-9
  • Molecular Formula: C24H21N3O4S2
  • Molecular Weight: 479.57
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
  • Create Date: 2022-08-13 16:54:37
  • Modify Date: 2024-08-05 13:13:17
  • EGFR/HER2/CDK9-IN-3 (Compound 10) is a potent inhibitor of EGFR/HER2/CDK9 with IC50s of 191.08, 132.65, and 113.98 nM, respectively. EGFR/HER2/CDK9-IN-3 exhibits remarkable antitumor activity[1].

Name EGFR/HER2/CDK9-IN-3
Description EGFR/HER2/CDK9-IN-3 (Compound 10) is a potent inhibitor of EGFR/HER2/CDK9 with IC50s of 191.08, 132.65, and 113.98 nM, respectively. EGFR/HER2/CDK9-IN-3 exhibits remarkable antitumor activity[1].
Related Catalog
References

[1]. El-Azab AS, et al. Antitumor activity, multitarget mechanisms, and molecular docking studies of quinazoline derivatives based on a benzenesulfonamide scaffold: Cell cycle analysis. Bioorg Chem. 2020;104:104345.

Molecular Formula C24H21N3O4S2
Molecular Weight 479.57
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