1345674-93-2

1345674-93-2 structure
1345674-93-2 structure
  • Name: Callophycin A
  • Chemical Name: Callophycin A
  • CAS Number: 1345674-93-2
  • Molecular Formula: C19H18N2O3
  • Molecular Weight: 322.36
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2022-08-17 18:52:55
  • Modify Date: 2024-01-04 11:35:56
  • Callophycin A, red seaweed derived metabolite, is potently against C. albicans. Callophycin A exhibits potent activity against drug resistance vaginal candidiasis[1].

Name Callophycin A
Description Callophycin A, red seaweed derived metabolite, is potently against C. albicans. Callophycin A exhibits potent activity against drug resistance vaginal candidiasis[1].
Related Catalog
Target

MIC: 62.5~250 mg/L (Candida albicans)[1]

In Vivo Callophycin A (1%; for 5 days) dramatically reduces CFU of Candida albicans; and significantly reduces the amount of IL-6, IL-12, IL-17 and IL-22 compared with disease control group[1]. Animal Model: Female Swiss albino mice (infected with Candida albicans)[1] Dosage: 1% Administration: For 5 days Result: Dramatically reduces CFU of Candida albicans from about 400 to 100/ml; and significantly (p < 0.001) reduces the amount of IL-6 (2.71 ± 0.09 to 1.83 ± 0.03 pg/µl), IL-12 (7.33 ± 0.15 to 6.13 ± 0.15 pg/µl), IL-17 (17.83 ± 0.21 to 13.70 ± 0.2 pg/µl) and IL-22 (5.33 ± 0.25 to 4.20 ± 0.26 pg/µl) compared with disease control group.
References

[1]. Arumugam Ganeshkumar, et al. New insight of red seaweed derived Callophycin A as an alternative strategy to treat drug resistance vaginal candidiasis. Bioorg Chem. 2020 Nov;104:104256.

Molecular Formula C19H18N2O3
Molecular Weight 322.36
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