Name | Callophycin A |
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Description | Callophycin A, red seaweed derived metabolite, is potently against C. albicans. Callophycin A exhibits potent activity against drug resistance vaginal candidiasis[1]. |
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Related Catalog | |
Target |
MIC: 62.5~250 mg/L (Candida albicans)[1] |
In Vivo | Callophycin A (1%; for 5 days) dramatically reduces CFU of Candida albicans; and significantly reduces the amount of IL-6, IL-12, IL-17 and IL-22 compared with disease control group[1]. Animal Model: Female Swiss albino mice (infected with Candida albicans)[1] Dosage: 1% Administration: For 5 days Result: Dramatically reduces CFU of Candida albicans from about 400 to 100/ml; and significantly (p < 0.001) reduces the amount of IL-6 (2.71 ± 0.09 to 1.83 ± 0.03 pg/µl), IL-12 (7.33 ± 0.15 to 6.13 ± 0.15 pg/µl), IL-17 (17.83 ± 0.21 to 13.70 ± 0.2 pg/µl) and IL-22 (5.33 ± 0.25 to 4.20 ± 0.26 pg/µl) compared with disease control group. |
References |
Molecular Formula | C19H18N2O3 |
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Molecular Weight | 322.36 |