2505339-54-6
2505339-54-6 structure
- Name: BR102910
- Chemical Name: BR102910
- CAS Number: 2505339-54-6
- Molecular Formula: C18H14Cl2F2N4O2S
- Molecular Weight: 459.30
- Catalog: Research Areas Metabolic Disease
- Create Date: 2022-08-15 22:33:34
- Modify Date: 2024-01-13 15:11:05
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BR102910 is a selective fibroblast activation protein (FAP) inhibitor with the IC50 of 2 nM. BR102910 also inhibits prolyl oligopeptidase (PREP) with the IC50 of 49.00 μM. BR102910 can be used for the researchof type 2
| Name | BR102910 |
|---|
| Description | BR102910 is a selective fibroblast activation protein (FAP) inhibitor with the IC50 of 2 nM. BR102910 also inhibits prolyl oligopeptidase (PREP) with the IC50 of 49.00 μM. BR102910 can be used for the researchof type 2 |
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| Related Catalog | |
| Target |
IC50: 2 nM (FAP), 49.0 μM (PREP), >100 μM (DPP-4)[1] |
| In Vivo | BR102910 (C57BL/6J mice, 0-30 mg/kg, Orally, once) shows significant FAP inhibition in a dose dependent manner[1]. Animal Model: C57BL/6J mice (n = 5 per group)[1] Dosage: 0, 10 and 30 mg/kg Administration: Orally, once Result: Showed significant FAP inhibition in a dose dependent manner. |
| References |
| Molecular Formula | C18H14Cl2F2N4O2S |
|---|---|
| Molecular Weight | 459.30 |