130222-84-3

130222-84-3 structure

Name: 5-O-(tert-Butyldiphenylsilyl)-2,3-isopropylidene-D-ribonolactone
Chemical Name: 5-o-tert-butyldiphenylsilyl-2,3-o-isopropylidene-d-lyxono-1,4-lactone
CAS Number: 130222-84-3
Molecular Formula: C₂₄H₃₀O₅Si
Molecular Weight: 426.58
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2022-08-16 18:08:16
Modify Date: 2025-09-01 08:03:08
5-O-(tert-Butyldiphenylsilyl)-2,3-isopropylidene-D-ribonolactone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-o-tert-butyldiphenylsilyl-2,3-o-isopropylidene-d-lyxono-1,4-lactone

Description	5-O-(tert-Butyldiphenylsilyl)-2,3-isopropylidene-D-ribonolactone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₂₄H₃₀O₅Si
Molecular Weight	426.58