2011801-48-0

2011801-48-0 structure

Name: PPARγ agonist 3
Chemical Name: PPARγ agonist 3
CAS Number: 2011801-48-0
Molecular Formula: C₂₄H₂₃N₃O
Molecular Weight: 369.46
Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
Create Date: 2022-07-02 21:02:55
Modify Date: 2024-01-02 22:35:26
PPARγ agonist 3 (Compound 18a) is a potent and selective agonist of PPARγ. PPARγ agonist 3 is not cytotoxic neither on non-resistant nor on resistant cells. PPARγ agonist 3 exerts antitumor potency only in combination with Imatinib[1].

Name	PPARγ agonist 3

Description	PPARγ agonist 3 (Compound 18a) is a potent and selective agonist of PPARγ. PPARγ agonist 3 is not cytotoxic neither on non-resistant nor on resistant cells. PPARγ agonist 3 exerts antitumor potency only in combination with Imatinib[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR
References	[1]. Schoepf AM, et al. Overcoming imatinib resistance in chronic myelogenous leukemia cells using non-cytotoxic cell death modulators. Eur J Med Chem. 2020 Jan 1;185:111748.

Molecular Formula	C₂₄H₂₃N₃O
Molecular Weight	369.46