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2396664-85-8

2396664-85-8 structure
2396664-85-8 structure
  • Name: FGFR4-IN-11
  • Chemical Name: FGFR4-IN-11
  • CAS Number: 2396664-85-8
  • Molecular Formula: C29H29N5O5
  • Molecular Weight: 527.57
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
  • Create Date: 2022-07-29 14:02:27
  • Modify Date: 2025-08-26 12:47:18
  • FGFR4-IN-11 (Compound 30) is a potent, selective, covalent FGFR4 inhibitor with an IC50 of 2.1 nM. FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and shows antitumor activity[1].
Name FGFR4-IN-11
Description FGFR4-IN-11 (Compound 30) is a potent, selective, covalent FGFR4 inhibitor with an IC50 of 2.1 nM. FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and shows antitumor activity[1].
Related Catalog
Target

FGFR4:2.1 nM (IC50)

References

[1]. Zhong Z, et al. Discovery of Novel 7-Azaindole Derivatives as Selective Covalent Fibroblast Growth Factor Receptor 4 Inhibitors for the Treatment of Hepatocellular Carcinoma. J Med Chem. 2022 May 26;65(10):7278-7295.
Molecular Formula C29H29N5O5
Molecular Weight 527.57
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title: CAS No. 2396664-85-8 | Chemsrc address: https://www.chemsrc.com/en/baike/1708199.html

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