2411741-01-8

2411741-01-8 structure

Name: Antituberculosis agent-2
Chemical Name: Antituberculosis agent-2
CAS Number: 2411741-01-8
Molecular Formula: C₁₉H₁₇NO₄
Molecular Weight: 323.34
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2022-07-01 12:33:48
Modify Date: 2024-01-21 13:03:56
Antituberculosis agent-2 (Compound 8d) is an antituberculosis agent against drug-sensitive and multidrug-resistant tuberculosis. Antituberculosis agent-2 shows anti-tuberculosis activity with MIC values of 0.454, 1.757 and 1.644 µg/mL against M. tuberculosis H37Rv, 13946 and 14862, respectively. Antituberculosis agent-2 displays favorable mouse and human microsomal stability, low cytotoxicity, and acceptable oral bioavailability[1].

Name	Antituberculosis agent-2

Description	Antituberculosis agent-2 (Compound 8d) is an antituberculosis agent against drug-sensitive and multidrug-resistant tuberculosis. Antituberculosis agent-2 shows anti-tuberculosis activity with MIC values of 0.454, 1.757 and 1.644 µg/mL against M. tuberculosis H37Rv, 13946 and 14862, respectively. Antituberculosis agent-2 displays favorable mouse and human microsomal stability, low cytotoxicity, and acceptable oral bioavailability[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Zhao W, et al. Design, synthesis, and biological evaluation of novel 4H-chromen-4-one derivatives as antituberculosis agents against multidrug-resistant tuberculosis. Eur J Med Chem. 2020 Mar 1;189:112075.

Molecular Formula	C₁₉H₁₇NO₄
Molecular Weight	323.34