2704617-93-4
2704617-93-4 structure
- Name: CFT8634
- Chemical Name: CFT8634
- CAS Number: 2704617-93-4
- Molecular Formula: C37H45F3N6O5
- Molecular Weight: 710.799
- Create Date: 2022-07-01 17:00:19
- Modify Date: 2024-01-02 19:59:36
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CFT-8634 (CFT8634) is a potent, selective, orally bioavailable BRD9 BiDAC degrader with DC50 of 3 nM, high selectivity over BRD4 abd BRD7.Unlike BRD9 inhibition, BRD9 degradation is efficacious in preclinical models of synovial sarcoma and CFT8634 is ongoing for the treatment of SMARCB1-perturbed cancers.
| Name | CFT8634 |
|---|
| Description | CFT-8634 (CFT8634) is a potent, selective, orally bioavailable BRD9 BiDAC degrader with DC50 of 3 nM, high selectivity over BRD4 abd BRD7.Unlike BRD9 inhibition, BRD9 degradation is efficacious in preclinical models of synovial sarcoma and CFT8634 is ongoing for the treatment of SMARCB1-perturbed cancers. |
|---|
| Molecular Formula | C37H45F3N6O5 |
|---|---|
| Molecular Weight | 710.799 |