1809336-90-0
1809336-90-0 structure
- Name: OR-S0
- Chemical Name: OR-S0
- CAS Number: 1809336-90-0
- Molecular Formula: C34H44N6O5
- Molecular Weight: 616.763
- Create Date: 2022-07-01 09:55:47
- Modify Date: 2024-01-20 11:02:59
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OR-S0 is a potent, selective EZH2 inhibitor with IC50 of 11 nM, weakly inhibitor EZH1 (IC50=91 nM).OR-S0 inhibits H3K27me3 in HCT116 cells with IC50 of 24 nM, inhibited the growth of KARPAS‐422 cells in a dose‐dependent manner with GI50 of 210 nM.
| Name | OR-S0 |
|---|
| Description | OR-S0 is a potent, selective EZH2 inhibitor with IC50 of 11 nM, weakly inhibitor EZH1 (IC50=91 nM).OR-S0 inhibits H3K27me3 in HCT116 cells with IC50 of 24 nM, inhibited the growth of KARPAS‐422 cells in a dose‐dependent manner with GI50 of 210 nM. |
|---|---|
| References | 1. Daisuke Honma, et al. Cancer Sci. 2017 Oct;108(10):2069-2078. |
| Molecular Formula | C34H44N6O5 |
|---|---|
| Molecular Weight | 616.763 |