880399-00-8

880399-00-8 structure

Name: GPVI antagonist 2
Chemical Name: GPVI antagonist 2
CAS Number: 880399-00-8
Molecular Formula: C₂₄H₂₇N₃O₄
Molecular Weight: 421.49
Catalog: Research Areas Cardiovascular Disease
Create Date: 2022-06-30 21:50:24
Modify Date: 2025-08-25 15:53:01
GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent[1].

Name	GPVI antagonist 2

Description	GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Olğaç S, et al. Identification of novel antiplatelet agents by targeting Glycoprotein VI: A combined virtual screening study. Bioorg Chem. 2022;121:105661.

Molecular Formula	C₂₄H₂₇N₃O₄
Molecular Weight	421.49