880399-00-8

880399-00-8 structure
880399-00-8 structure
  • Name: GPVI antagonist 2
  • Chemical Name: GPVI antagonist 2
  • CAS Number: 880399-00-8
  • Molecular Formula: C24H27N3O4
  • Molecular Weight: 421.49
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2022-06-30 21:50:24
  • Modify Date: 2024-01-15 05:55:42
  • GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent[1].

Name GPVI antagonist 2
Description GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent[1].
Related Catalog
References

[1]. Olğaç S, et al. Identification of novel antiplatelet agents by targeting Glycoprotein VI: A combined virtual screening study. Bioorg Chem. 2022;121:105661.

Molecular Formula C24H27N3O4
Molecular Weight 421.49