GPVI antagonist 2

Modify Date: 2025-08-25 15:53:01

GPVI antagonist 2 Structure
GPVI antagonist 2 structure
Common Name GPVI antagonist 2
CAS Number 880399-00-8 Molecular Weight 421.49
Density N/A Boiling Point N/A
Molecular Formula C24H27N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GPVI antagonist 2


GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent[1].

 Names

Name GPVI antagonist 2

 GPVI antagonist 2 Biological Activity

Description GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent[1].
Related Catalog
References

[1]. Olğaç S, et al. Identification of novel antiplatelet agents by targeting Glycoprotein VI: A combined virtual screening study. Bioorg Chem. 2022;121:105661.

 Chemical & Physical Properties

Molecular Formula C24H27N3O4
Molecular Weight 421.49
InChIKey CLSMBWZDZBUGAX-UHFFFAOYSA-N
SMILES CCCCOc1cccc(C2C3C(NNC3c3ccccc3O)C(=O)N2CCCO)c1
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