2756350-98-6
2756350-98-6 structure
- Name: CCR8 antagonist 2
- Chemical Name: CCR8 antagonist 2
- CAS Number: 2756350-98-6
- Molecular Formula: C23H30ClN3O3S
- Molecular Weight: 464.02
- Catalog: Signaling Pathways GPCR/G Protein CCR
- Create Date: 2022-06-30 18:16:09
- Modify Date: 2025-08-24 20:10:54
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CCR8 antagonist 2 is a potent antagonist of CCR8. CCR8 (C-C Motif Chemokine Receptor 8) is predominantly expressed on Treg cells and Th2 cells, but not on Th1 cells. CCR8 antagonist 2 inhibits CCR8 activity, which may be used in the treatment of diseases mediated by CCR8, such as cancer, and/or neuropathic pain (extracted from patent WO2022000443A1, compound 220)[1].
| Name | CCR8 antagonist 2 |
|---|
| Description | CCR8 antagonist 2 is a potent antagonist of CCR8. CCR8 (C-C Motif Chemokine Receptor 8) is predominantly expressed on Treg cells and Th2 cells, but not on Th1 cells. CCR8 antagonist 2 inhibits CCR8 activity, which may be used in the treatment of diseases mediated by CCR8, such as cancer, and/or neuropathic pain (extracted from patent WO2022000443A1, compound 220)[1]. |
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| Related Catalog | |
| References |
[1]. Guohuang FAN, et al. Methods and compositions for targeting tregs using ccr8 inhibitors. |
| Molecular Formula | C23H30ClN3O3S |
|---|---|
| Molecular Weight | 464.02 |