2115702-83-3

2115702-83-3 structure

Name: TLR7/8 agonist 6
Chemical Name: TLR7/8 agonist 6
CAS Number: 2115702-83-3
Molecular Formula: C₂₄H₂₇N₅O₂
Molecular Weight: 417.50
Create Date: 2022-05-15 07:19:44
Modify Date: 2025-09-18 23:24:23
TLR7/8 agonist 6 (Compound 4) is the potent agonist of TLR7/8 with IC50s of 0.18 and 5.34 μM, respectively. TLR7/8 agonist 6 is an imidazoquinoline derivative compound. Toll-like receptors (TLRs) 7 and 8 are key targets in the development of immunomodulatory drugs for treating infectious disease, cancer, and autoimmune disorders[1].

Name	TLR7/8 agonist 6

Description	TLR7/8 agonist 6 (Compound 4) is the potent agonist of TLR7/8 with IC50s of 0.18 and 5.34 μM, respectively. TLR7/8 agonist 6 is an imidazoquinoline derivative compound. Toll-like receptors (TLRs) 7 and 8 are key targets in the development of immunomodulatory drugs for treating infectious disease, cancer, and autoimmune disorders[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Cancer Research Areas >> Infection Research Areas >> Inflammation/Immunology
References	[1]. Yang M, et al. Toll-like receptor 7 and 8 imidazoquinoline-based agonist/antagonist pairs. Bioorg Med Chem Lett. 2022;59:128548.

Molecular Formula	C₂₄H₂₇N₅O₂
Molecular Weight	417.50