2755843-62-8
2755843-62-8 structure
- Name: RET-IN-14
- Chemical Name: RET-IN-14
- CAS Number: 2755843-62-8
- Molecular Formula: C24H23FN8O4
- Molecular Weight: 506.49
- Create Date: 2022-06-01 15:08:37
- Modify Date: 2025-09-12 16:56:51
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RET-IN-14 (compound 49) is a potent RET inhibitor with IC50s of <0.51 nM, 9.3 nM, 1.3 nM, 9.2 nM, 15 nM for RET (WT), RET (G810R), RET (V804M), BTK and BTK (C481S), respectively. RET-IN-14 has the potential for tumors research[1]
| Name | RET-IN-14 |
|---|
| Description | RET-IN-14 (compound 49) is a potent RET inhibitor with IC50s of <0.51 nM, 9.3 nM, 1.3 nM, 9.2 nM, 15 nM for RET (WT), RET (G810R), RET (V804M), BTK and BTK (C481S), respectively. RET-IN-14 has the potential for tumors research[1] |
|---|---|
| Related Catalog | |
| References |
[1]. Jing Wang, et al. Compounds with macrocyclic structure and their uses. WO2021244609A1. |
| Molecular Formula | C24H23FN8O4 |
|---|---|
| Molecular Weight | 506.49 |