2237925-62-9

2237925-62-9 structure

Name: DMA-135 hydrochloride
Chemical Name: DMA-135 hydrochloride
CAS Number: 2237925-62-9
Molecular Formula: C₁₆H₁₈ClN₇O
Molecular Weight: 359.81
Create Date: 2022-05-30 18:20:46
Modify Date: 2024-04-03 19:42:22
DMA-135 hydrochloride inhibits enterovirus 71 (EV71) IRES-dependent translation and replication. DMA-135 hydrochloride binds to enterovirus 71 (EV71) SLII domain with moderately high affinity (KD= 520 nM). DMA-135 hydrochloride has no significant toxicity in cell-based studies[1].

Name	DMA-135 hydrochloride

Description	DMA-135 hydrochloride inhibits enterovirus 71 (EV71) IRES-dependent translation and replication. DMA-135 hydrochloride binds to enterovirus 71 (EV71) SLII domain with moderately high affinity (KD= 520 nM). DMA-135 hydrochloride has no significant toxicity in cell-based studies[1].
Related Catalog	Research Areas >> Infection
References	[1]. Davila-Calderon J, Patwardhan NN, Chiu LY, et al. IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex. Nat Commun. 2020;11(1):4775. Published 2020 Sep 22.

Molecular Formula	C₁₆H₁₈ClN₇O
Molecular Weight	359.81