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203850-92-4

203850-92-4 structure
203850-92-4 structure
  • Name: 5a-Pregnane-3,20-dione-d6
  • Chemical Name: 5a-Pregnane-3,20-dione-d6
  • CAS Number: 203850-92-4
  • Molecular Formula: C21H26D6O2
  • Molecular Weight: 322.51
  • Create Date: 2022-05-15 11:07:17
  • Modify Date: 2024-01-12 09:13:35
  • 5a-Pregnane-3,20-dione-d6 is the deuterium labeled 5a-Pregnane-3,20-dione. 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

Name 5a-Pregnane-3,20-dione-d6
Description 5a-Pregnane-3,20-dione-d6 is the deuterium labeled 5a-Pregnane-3,20-dione. 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Wiebe JP, et al. The endogenous progesterone metabolite, 5a-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells. Endocrine. 2001 Oct;16(1):7-14.

Molecular Formula C21H26D6O2
Molecular Weight 322.51
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