2639542-32-6

2639542-32-6 structure

Name: CDK5-IN-3
Chemical Name: CDK5-IN-3
CAS Number: 2639542-32-6
Molecular Formula: C₂₂H₂₆N₄O
Molecular Weight: 362.47
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2022-04-29 08:52:48
Modify Date: 2024-01-14 18:38:55
CDK5-IN-3 (compound 11) is a potent and selective CDK5 inhibitor, with IC50s of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. CDK5-IN-3 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD)[1].

Name	CDK5-IN-3

Description	CDK5-IN-3 (compound 11) is a potent and selective CDK5 inhibitor, with IC50s of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. CDK5-IN-3 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD)[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> CDK Research Areas >> Metabolic Disease
Target	Cdk5/p25:0.6 nM (IC50) CDK2/CycA:18 nM (IC50)
References	[1]. Discovery and Optimization of Highly Selective Inhibitors of CDK5. J Med Chem. 2022 Feb 24;65(4):3575-3596.

Molecular Formula	C₂₂H₂₆N₄O
Molecular Weight	362.47