1625629-51-7

1625629-51-7 structure
1625629-51-7 structure
  • Name: MCAAD-3
  • Chemical Name: MCAAD-3
  • CAS Number: 1625629-51-7
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2022-03-28 08:54:28
  • Modify Date: 2025-09-11 12:53:54
  • MCAAD-3 is a near-infrared Aβ imaging probe with blood-brain barrier penetrability. MCAAD-3 has a strong affinity for Aβ polymers (Ki >106 nM) and can label Aβ plaques in the brains of transgenic mice[1].

Name MCAAD-3
Synonyms methyl(2Z,4E,6E)-2-cyano-7-[4-(dimethylamino)]hepta-2,4,6-trienoate
Description MCAAD-3 is a near-infrared Aβ imaging probe with blood-brain barrier penetrability. MCAAD-3 has a strong affinity for Aβ polymers (Ki >106 nM) and can label Aβ plaques in the brains of transgenic mice[1].
Related Catalog
References

[1]. Fu H, et al. Evaluation of molecules based on the electron donor-acceptor architecture as near-infrared β-amyloidal-targeting probes. Chem Commun (Camb). 2014 Oct 14;50(80):11875-8.  

Water Solubility Soluble in DMSO to 100 mM
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