1507095-58-0

1507095-58-0 structure

Name: TWS119 TFA
Chemical Name: TWS 119
CAS Number: 1507095-58-0
Molecular Formula: C₁₈H₁₄N₄O_2.2CF₃CO₂H
Molecular Weight: 546.38
Catalog: Research Areas Others
Create Date: 2022-03-20 21:57:24
Modify Date: 2025-10-20 18:58:21
TWS119 TFA is a specific inhibitor of GSK-3β, with an IC50 of 30 nM, and activates the wnt/β-catenin pathway.

Name	TWS 119
Synonyms	MFCD18086896 Acetic acid, 2,2,2-trifluoro-, compd. with 3-[[6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenol (2:1) 3-{[6-(3-Aminophenyl)-1H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy}phenol trifluoroacetate (1:2) 3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxyphenol ditrifluoroacetate MFCD09037535

Description	TWS119 TFA is a specific inhibitor of GSK-3β, with an IC50 of 30 nM, and activates the wnt/β-catenin pathway.
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. HochstrasserRM. Two-dimensional spectroscopy at infrared and optical frequencies. Proc NatlAcad Sci U S A. 2007 Sep 4;104(36):14190-6. [2]. Hochstrasser RM. Two-dimensional spectroscopy at infrared and optical frequencies. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14190-6.