85916-13-8

85916-13-8 structure

Name: Di-tert-butyl iminodiacetate
Chemical Name: tert-butyl 2-[[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]amino]acetate
CAS Number: 85916-13-8
Molecular Formula: C₁₂H₂₃NO₄
Molecular Weight: 245.315
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-04-13 08:00:00
Modify Date: 2025-08-24 15:08:26
NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC).

Name	tert-butyl 2-[[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]amino]acetate
Synonyms	MFCD01863672 nitrilodiacetic acid di-tert-butyl ester (tert-butoxycarbonylmethyl-amino)-acetic acid tert-butyl ester Bis(2-methyl-2-propanyl) 2,2'-iminodiacetate aminodiacetic acid di-tert-butyl ester Di-tert-butyl iminodiacetate di-tert-butyl 2,2'-iminodiacetate HN(CH2CO2-tBu)2 iminodiacetic acid di-tert-butyl ester Glycine, N-[2-(1,1-dimethylethoxy)-2-oxoethyl]-, 1,1-dimethylethyl ester Di-tert-butyl iminodiacetate

Description	NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC).
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Noncleavable

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	26-36/37/39
RIDADR	NONH for all modes of transport

275371-57-8

~95%

85916-13-8

Literature: Journal of Organic Chemistry, , vol. 68, # 10 p. 3999 - 4007

100-20-9

75-65-0

85916-13-8

Literature: EP369391 A3, ;

5292-43-3

58482-93-2

~33%

85916-13-8

Literature: US2012/149632 A1, ;

5292-43-3

85916-13-8

Literature: Journal of Organic Chemistry, , vol. 68, # 10 p. 3999 - 4007

142-73-4

75-65-0

~52%

85916-13-8

Literature: Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 42, # 6 p. 373 - 377

540-88-5

142-73-4

~37%

85916-13-8

Literature: Tetrahedron Letters, , vol. 33, # 42 p. 6303 - 6306