2468015-78-1
2468015-78-1 structure
- Name: Lufotrelvir (PF-07304814)
- Chemical Name: Lufotrelvir
- CAS Number: 2468015-78-1
- Molecular Formula: C24H33N4O9P
- Molecular Weight: 552.51
- Create Date: 2022-01-04 16:32:43
- Modify Date: 2025-08-25 18:53:36
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Lufotrelvir (PF-07304814), a phosphate prodrug of PF-00835231, acts as a potent 3CLpro protease (Mpro) inhibitor with SARS-CoV-2 antiviral activity. Lufotrelvir binds and inhibits SARS-CoV-2 3CLpro activity with a Ki of 174nM. Lufotrelvir is promising single antiviral agent and also can be used for the research of combination with other antivirals that target other critical stages of the coronavirus life cycle.
| Name | Lufotrelvir |
|---|
| Description | Lufotrelvir (PF-07304814), a phosphate prodrug of PF-00835231, acts as a potent 3CLpro protease (Mpro) inhibitor with SARS-CoV-2 antiviral activity. Lufotrelvir binds and inhibits SARS-CoV-2 3CLpro activity with a Ki of 174nM. Lufotrelvir is promising single antiviral agent and also can be used for the research of combination with other antivirals that target other critical stages of the coronavirus life cycle. |
|---|
| Molecular Formula | C24H33N4O9P |
|---|---|
| Molecular Weight | 552.51 |
| Storage condition | -20°C |