40313-92-6
40313-92-6 structure
- Name: Thalidomide-5-methyl
- Chemical Name: Thalidomide-5-methyl
- CAS Number: 40313-92-6
- Molecular Formula: C14H12N2O4
- Molecular Weight: 272.26
- Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
- Create Date: 2021-12-20 00:13:32
- Modify Date: 2025-08-26 19:09:24
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Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].
| Name | Thalidomide-5-methyl |
|---|
| Description | Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1]. |
|---|---|
| Related Catalog | |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C14H12N2O4 |
|---|---|
| Molecular Weight | 272.26 |