872113-12-7

872113-12-7 structure

Name: TCMDC-125457
Chemical Name: TCMDC-125457
CAS Number: 872113-12-7
Molecular Formula: C₁₉H₁₈ClN₅O₃
Molecular Weight: 399.83
Catalog: Research Areas Infection
Create Date: 2022-01-06 10:21:00
Modify Date: 2025-08-25 22:51:46
TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.

Name	TCMDC-125457

Description	TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.
References	[1]. Chia W, et al. High-Content Phenotypic Screen of a Focused TCAMS Drug Library Identifies Novel Disruptors of the Malaria Parasite Calcium Dynamics. ACS Chem Biol. 2021 Nov 19;16(11):2348-2372.

Molecular Formula	C₁₉H₁₈ClN₅O₃
Molecular Weight	399.83