1450666-97-3
1450666-97-3 structure
- Name: MMV666810
- Chemical Name: MMV666810
- CAS Number: 1450666-97-3
- Molecular Formula: C23H21F3N4O2
- Molecular Weight: 442.43
- Catalog: Research Areas Infection
- Create Date: 2022-04-04 23:25:31
- Modify Date: 2024-04-11 18:22:13
-
MMV666810, a 2-aminopyrazine similar to MMV390048, is potent against asexual parasites at 5.94 nM, but against gametocytes, it has a 3.3-fold selectivity to late-stage gametocytes compared to earlier stages (early-stage gametocyte: IC50 603 ± 88 nM; late-stage gametocyte: IC50 179 ± 8 nM).
| Name | MMV666810 |
|---|
| Description | MMV666810, a 2-aminopyrazine similar to MMV390048, is potent against asexual parasites at 5.94 nM, but against gametocytes, it has a 3.3-fold selectivity to late-stage gametocytes compared to earlier stages (early-stage gametocyte: IC50 603 ± 88 nM; late-stage gametocyte: IC50 179 ± 8 nM). |
|---|---|
| References |
| Molecular Formula | C23H21F3N4O2 |
|---|---|
| Molecular Weight | 442.43 |