932708-14-0

932708-14-0 structure

Name: Pexopiprant
Chemical Name: {[8-Chloro-3-(4-chlorobenzyl)-4-(difluoromethoxy)-2-ethyl-5-quinolinyl]oxy}acetic acid
CAS Number: 932708-14-0
Molecular Formula: C₂₁H₁₇Cl₂F₂NO₄
Molecular Weight: 456.27
Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
Create Date: 2021-12-28 18:27:15
Modify Date: 2023-01-11 17:27:39
Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki ＜ 100nM. Pexopiprant can be used in studies of asthma[1].

Name	{[8-Chloro-3-(4-chlorobenzyl)-4-(difluoromethoxy)-2-ethyl-5-quinolinyl]oxy}acetic acid
Synonyms	{[8-Chloro-3-(4-chlorobenzyl)-4-(difluoromethoxy)-2-ethyl-5-quinolinyl]oxy}acetic acid Acetic acid, 2-[[8-chloro-3-[(4-chlorophenyl)methyl]-4-(difluoromethoxy)-2-ethyl-5-quinolinyl]oxy]-

Description	Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki ＜ 100nM. Pexopiprant can be used in studies of asthma[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
Target	hDP2:<100 nM (Ki)
References	[1]. Cramp, Michael Colin; Arienzo, Rosa; Hynd, George; Crackett, Peter; Griffon, Yann; Harrison, Trevor Keith; Ray, Nicholas Charles; Finch, Harry; Montana, John Gary.Preparation of quinoline derivatives as CRTH2 antagonists. WO2007036743 A2.