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37308-75-1

37308-75-1 structure
37308-75-1 structure
  • Name: Flavokawain C
  • Chemical Name: (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
  • CAS Number: 37308-75-1
  • Molecular Formula: C17H16O5
  • Molecular Weight: 300.306
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2018-07-06 13:23:11
  • Modify Date: 2024-01-02 16:47:22
  • Flavokawain C is a natural chalcone found in Kava root. Flavokawain C exerts cytotoxicity against human cancer cell lines, with an IC50 of 12.75 μM for HCT 116 cells[1].
Name (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
Synonyms 4',6'-dimethoxy-2',4-dihydroxychalcone
Flavokavain C
1-(2-hydroxy-4,6-dimethoxy)phenyl-3-(4-hydroxy)phenyl-2-propen-1-one
2',4-Dihydroxy-4',6'-dimethoxychalcone
2'-hydroxy-4,6'-dimethoxychalcone
2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-
(E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
2299311
(2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
Flavokawain C
Flavokawin C
flavokawin
(2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
QR D1U1VR BQ DO1 FO1 &&E Form
4',6'-di-O-methylchalconaringenin
Description Flavokawain C is a natural chalcone found in Kava root. Flavokawain C exerts cytotoxicity against human cancer cell lines, with an IC50 of 12.75 μM for HCT 116 cells[1].
Related Catalog
References

[1]. Phang CW, et al. Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells. PLoS One. 2016 Feb 9;11(2):e0148775.
Density 1.3±0.1 g/cm3
Boiling Point 556.0±50.0 °C at 760 mmHg
Melting Point 179-182℃
Molecular Formula C17H16O5
Molecular Weight 300.306
Flash Point 207.3±23.6 °C
Exact Mass 300.099762
PSA 75.99000
LogP 3.48
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.637
90-24-4 structure

90-24-4
123-08-0 structure

123-08-0

~33%

37308-75-1 structure

37308-75-1
Literature: Seo, Young Ho; Park, Sun You Bulletin of the Korean Chemical Society, 2014 , vol. 35, # 4 p. 1154 - 1158
77184-69-1 structure

77184-69-1

~69%

37308-75-1 structure

37308-75-1
Literature: Vogel, Susanne; Heilmann, Joerg Journal of Natural Products, 2008 , vol. 71, # 7 p. 1237 - 1241
62014-87-3 structure

62014-87-3
74-88-4 structure

74-88-4

~%

37308-75-1 structure

37308-75-1
Literature: Morimoto, Masanori; Kumeda, Sumiko; Komai, Koichiro Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 5 p. 1888 - 1891
480-66-0 structure

480-66-0

~%

37308-75-1 structure

37308-75-1
Literature: Seo, Young Ho; Park, Sun You Bulletin of the Korean Chemical Society, 2014 , vol. 35, # 4 p. 1154 - 1158

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title: CAS No. 37308-75-1 | Chemsrc address: https://www.chemsrc.com/en/baike/168470.html

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