1159408-54-4

1159408-54-4 structure

Name: TLR4-IN-C34-C2-COOH
Chemical Name: 5-[(3,4,6-Tri-O-acetyl-2-acetylamido-2-deoxy-b-D-galactopyranosyl)oxy]pentanoic acid
CAS Number: 1159408-54-4
Molecular Formula: C₁₉H₂₉NO₁₁
Molecular Weight: 447.43
Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
Create Date: 2021-11-04 11:37:26
Modify Date: 2025-08-25 14:51:40
TLR4-IN-C34-C2-COO is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis[1].

Name	5-[(3,4,6-Tri-O-acetyl-2-acetylamido-2-deoxy-b-D-galactopyranosyl)oxy]pentanoic acid
Synonyms	5-[(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-galactopyranosyl)oxy]pentanoic acid MFCD30802159 Pentanoic acid, 5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-

Description	TLR4-IN-C34-C2-COO is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Inflammation/Immunology Signaling Pathways >> PROTAC >> PROTAC Linker
References	[1]. Neal MD, et al. Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One. 2013;8(6):e65779. Published 2013 Jun 12.

Density	1.29±0.1 g/cm3(Predicted)
Boiling Point	634.1±55.0 °C(Predicted)
Molecular Formula	C₁₉H₂₉NO₁₁
Molecular Weight	447.43
Flash Point	337.3±31.5 °C
Exact Mass	447.174072
LogP	0.27
Vapour Pressure	0.0±4.0 mmHg at 25°C
Index of Refraction	1.505
Storage condition	Inert atmosphere,Store in freezer, under -20°C

Hazard Codes	Xi