85577-28-2

85577-28-2 structure

Name: Zomepirac-d4 sodium salt
Chemical Name: Zomepirac-d4 sodium salt
CAS Number: 85577-28-2
Molecular Formula: C₁₅H₁₀D₄ClNNaO₃
Molecular Weight: 317.74
Catalog: Signaling Pathways Immunology/Inflammation PGE synthase
Create Date: 2021-10-25 17:19:24
Modify Date: 2023-05-20 19:07:46
Zomepirac-d4 sodium salt is the deuterium labeled Zomepirac sodium salt. Zomepirac sodium salt (McN-2783-21-98) is a potent prostaglandin biosynthesis inhibitor. Zomepirac sodium salt is a non-steroidal anti-inflammatory drug (NSAID). Zomepirac sodium salt can cause immune-mediated liver injury[1][2].

Name	Zomepirac-d4 sodium salt

Description	Zomepirac-d4 sodium salt is the deuterium labeled Zomepirac sodium salt. Zomepirac sodium salt (McN-2783-21-98) is a potent prostaglandin biosynthesis inhibitor. Zomepirac sodium salt is a non-steroidal anti-inflammatory drug (NSAID). Zomepirac sodium salt can cause immune-mediated liver injury[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> PGE synthase
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Min Wang, et al. Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse. J Gastroenterol Hepatol. 2002 Jan;17(1):66-71. [3]. T P Pruss, et al. Evaluation of the analgesic properties of zomepirac. J Clin Pharmacol. 1980 Apr;20(4):216-22.

Molecular Formula	C₁₅H₁₀D₄ClNNaO₃
Molecular Weight	317.74