2509360-22-7
2509360-22-7 structure
- Name: Thalidomide-O-C3-NH2
- Chemical Name: Thalidomide-O-C3-NH2
- CAS Number: 2509360-22-7
- Molecular Formula: C16H17N3O5
- Molecular Weight: 331.32
- Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
- Create Date: 2021-09-12 11:01:11
- Modify Date: 2024-01-09 18:10:18
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Thalidomide-O-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
| Name | Thalidomide-O-C3-NH2 |
|---|
| Description | Thalidomide-O-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
|---|---|
| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C16H17N3O5 |
|---|---|
| Molecular Weight | 331.32 |
| Hazard Codes | Xi |
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