2271036-45-2

2271036-45-2 structure

Name: Pomalidomide 4'-PEG2-azide
Chemical Name: Pomalidomide 4'-PEG2-azide
CAS Number: 2271036-45-2
Molecular Formula: C₁₉H₂₂N₆O₆
Molecular Weight: 430.41
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2021-09-11 00:02:00
Modify Date: 2024-01-12 21:10:21
Pomalidomide 4'-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].

Name	Pomalidomide 4'-PEG2-azide

Description	Pomalidomide 4'-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₉H₂₂N₆O₆
Molecular Weight	430.41

Hazard Codes	Xi