1280215-91-9

1280215-91-9 structure
1280215-91-9 structure
  • Name: Lys-Nε-SPDB-DM4
  • Chemical Name: Lys-Nε-SPDB-DM4
  • CAS Number: 1280215-91-9
  • Molecular Formula: C48H72ClN5O13S2
  • Molecular Weight: 1026.69
  • Catalog: Research Areas Cancer
  • Create Date: 2021-09-12 20:07:04
  • Modify Date: 2025-08-25 18:30:34
  • Lys-Nε-SPDB-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Lys-Nε-SPDB to make antibody drug conjugate (ADC)[1].

Name Lys-Nε-SPDB-DM4
Description Lys-Nε-SPDB-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Lys-Nε-SPDB to make antibody drug conjugate (ADC)[1].
Related Catalog
Target

Maytansinoids

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Hans K Erickson, et al. Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing. Cancer Res. 2006 Apr 15;66(8):4426-33.

Molecular Formula C48H72ClN5O13S2
Molecular Weight 1026.69
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.