2468780-87-0
2468780-87-0 structure
- Name: Lenalidomide-6-F
- Chemical Name: Lenalidomide-6-F
- CAS Number: 2468780-87-0
- Molecular Formula: C13H11FN2O3
- Molecular Weight: 262.24
- Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
- Create Date: 2021-09-09 19:39:23
- Modify Date: 2024-01-06 14:14:18
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Lenalidomide-6-F is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-6-F can be connected to the ligand for protein by a linker to form PROTAC[1].
| Name | Lenalidomide-6-F |
|---|
| Description | Lenalidomide-6-F is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-6-F can be connected to the ligand for protein by a linker to form PROTAC[1]. |
|---|---|
| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C13H11FN2O3 |
|---|---|
| Molecular Weight | 262.24 |
| Hazard Codes | Xi |
|---|