2457357-99-0
2457357-99-0 structure
- Name: FNC-TP
- Chemical Name: FNC-TP
- CAS Number: 2457357-99-0
- Molecular Formula: C9H14FN6O13P3
- Molecular Weight: 526.16
- Catalog: Signaling Pathways Anti-infection HBV
- Create Date: 2021-09-14 17:37:13
- Modify Date: 2024-01-09 20:19:25
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FNC-TP is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV[1].
| Name | FNC-TP |
|---|
| Description | FNC-TP is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV[1]. |
|---|---|
| Related Catalog | |
| Target |
reverse transcriptase[1] HIV[1] HBV[1] HCV[1] |
| In Vitro | FNC (0.1-10 nM; 24-240 h) is found mainly to accumulate in these HIV-1 target cells, and the retention of FNC-TP is 2-4 times higher than in other types of cells[1]. |
| In Vivo | FNC (1-6 mg/kg; a single p.o.) could enter rhesus macaque PBMCs and form the active nucleoside triphosphate FNC-TP[1]. |
| References |
| Molecular Formula | C9H14FN6O13P3 |
|---|---|
| Molecular Weight | 526.16 |