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1948229-21-7

1948229-21-7 structure
1948229-21-7 structure
  • Name: Eliapixant
  • Chemical Name: Eliapixant
  • CAS Number: 1948229-21-7
  • Molecular Formula: C22H21F3N4O3S
  • Molecular Weight: 478.49
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel P2X Receptor
  • Create Date: 2021-09-06 11:14:56
  • Modify Date: 2024-01-05 12:42:47
  • Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough[1][2].

Name Eliapixant
Description Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough[1][2].
Related Catalog
Target

IC50: 8 nM (P2X3 receptor)[1]

In Vivo Eliapixant can be used for the research of coughs and diabetes complications[1].
References

[1]. Spinaci A, et, al. P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications. Front Pharmacol. 2021 Apr 13;12:653561.

[2]. Morice A, et, al. Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study. Eur Respir J. 2021 May 13;2004240.

Density 1.360±0.06 g/cm3(Predicted)
Molecular Formula C22H21F3N4O3S
Molecular Weight 478.49
Storage condition -20°C
Hazard Codes Xn