2169266-69-5
2169266-69-5 structure
- Name: Thalidomide-O-C6-COOH
- Chemical Name: Thalidomide-O-C6-COOH
- CAS Number: 2169266-69-5
- Molecular Formula: C20H22N2O7
- Molecular Weight: 402.40
- Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
- Create Date: 2021-09-12 01:01:38
- Modify Date: 2025-10-10 00:27:35
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Thalidomide-O-C6-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
| Name | Thalidomide-O-C6-COOH |
|---|---|
| Synonyms | MFCD32063464 |
| Description | Thalidomide-O-C6-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
|---|---|
| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C20H22N2O7 |
|---|---|
| Molecular Weight | 402.40 |
| Hazard Codes | Xi |
|---|