55446-15-6

55446-15-6 structure
55446-15-6 structure
  • Name: Araloside C
  • Chemical Name: Araloside C
  • CAS Number: 55446-15-6
  • Molecular Formula: C53H84O23
  • Molecular Weight: 1089.22
  • Catalog: Research Areas Others
  • Create Date: 2021-09-12 20:14:39
  • Modify Date: 2024-01-14 14:53:56
  • Araloside C exhibits protective effects against myocardial ischaemia/reperfusion injury[1].

Name Araloside C
Description Araloside C exhibits protective effects against myocardial ischaemia/reperfusion injury[1].
Related Catalog
In Vitro Araloside C also up-regulates the expression levels of Hsp90 and improved cell viability in hypoxia/reoxygenation-treated H9c2 cardiomyocytes, whereas the addition of 17-AAG, a pharmacologic inhibitor of Hsp90, attenuates Araloside C-induced cardioprotective effect[1]. Araloside C (0.5-2.5 μM) concentration-dependently improves the functional recovery of the I/R hearts, including increase in the recovery of LVDP, dP/dtmax and heart rate throughout the reperfusion period, although the baseline mechanical parameters with Araloside C were not significantly different compared with those of the control condition[1]. Araloside C could improve post-ischaemic cell shortening and Ca2+ transients from 2 to 8 μM[1].
References

[1]. Min Wang, et al. Protective effects of Araloside C against myocardial ischaemia/reperfusion injury: potential involvement of heat shock protein 90. J Cell Mol Med. 2017 Sep;21(9):1870-1880.

Molecular Formula C53H84O23
Molecular Weight 1089.22