Name | Araloside C |
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Description | Araloside C exhibits protective effects against myocardial ischaemia/reperfusion injury[1]. |
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Related Catalog | |
In Vitro | Araloside C also up-regulates the expression levels of Hsp90 and improved cell viability in hypoxia/reoxygenation-treated H9c2 cardiomyocytes, whereas the addition of 17-AAG, a pharmacologic inhibitor of Hsp90, attenuates Araloside C-induced cardioprotective effect[1]. Araloside C (0.5-2.5 μM) concentration-dependently improves the functional recovery of the I/R hearts, including increase in the recovery of LVDP, dP/dtmax and heart rate throughout the reperfusion period, although the baseline mechanical parameters with Araloside C were not significantly different compared with those of the control condition[1]. Araloside C could improve post-ischaemic cell shortening and Ca2+ transients from 2 to 8 μM[1]. |
References |
Molecular Formula | C53H84O23 |
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Molecular Weight | 1089.22 |