67292-68-6

67292-68-6 structure

Name: 2-(5-methoxy-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine
Chemical Name: 2-(5-methoxy-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine
CAS Number: 67292-68-6
Molecular Formula: C₁₄H₂₀N₂O
Molecular Weight: 232.32100
Create Date: 2018-12-25 17:25:30
Modify Date: 2024-01-02 18:40:27

Name	2-(5-methoxy-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine
Synonyms	2-methyl-5-methoxy-N,N-dimethyltryptamine Methyl-2-methoxy-5-N-dimethyltryptamine 4365 CT

Density	1.079g/cm3
Boiling Point	383.7ºC at 760 mmHg
Molecular Formula	C₁₄H₂₀N₂O
Molecular Weight	232.32100
Flash Point	185.8ºC
Exact Mass	232.15800
PSA	28.26000
LogP	2.58900
Index of Refraction	1.589

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL7400000

CHEMICAL NAME :: Indole, 3-(2-(dimethylamino)ethyl)-5-methoxy-2-methyl-

CAS REGISTRY NUMBER :: 67292-68-6

BEILSTEIN REFERENCE NO. :: 0179917

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C14-H20-N2-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 74 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSCFAS Bulletin de la Societe Chimique de France. (CDR-Centrale des Revues, 11, rue Gossin, F-92543 Montrouge Cedex, France) V.1- 1864- Volume(issue)/page/year: (5),1411,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSCFAS Bulletin de la Societe Chimique de France. (CDR-Centrale des Revues, 11, rue Gossin, F-92543 Montrouge Cedex, France) V.1- 1864- Volume(issue)/page/year: (5),1411,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 48 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSCFAS Bulletin de la Societe Chimique de France. (CDR-Centrale des Revues, 11, rue Gossin, F-92543 Montrouge Cedex, France) V.1- 1864- Volume(issue)/page/year: (5),1411,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 22 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSCFAS Bulletin de la Societe Chimique de France. (CDR-Centrale des Revues, 11, rue Gossin, F-92543 Montrouge Cedex, France) V.1- 1864- Volume(issue)/page/year: (5),1411,1965

79098-38-7

19501-58-7

~77%

67292-68-6

Literature: SUVEN LIFE SCIENCES LIMITED Patent: WO2004/41781 A1, 2004 ; Location in patent: Page 11 ;

28089-03-4

~79%

67292-68-6

Literature: Merck Sharp and Dohme Ltd. Patent: US6187805 B1, 2001 ; US 6187805 B1

50-00-0

28089-03-4

~79%

67292-68-6

Literature: Russell; Baker; Barden; Beer; Bristow; Broughton; Knowles; McAllister; Patel; Castro Journal of Medicinal Chemistry, 2001 , vol. 44, # 23 p. 3881 - 3895

100722-77-8

67292-68-6

Literature: Shaw Journal of the American Chemical Society, 1955 , vol. 77, p. 4319,4320 Journal of the American Chemical Society, 1956 , vol. 78, p. 6419

1076-74-0

67292-68-6

Literature: Vermeulen, Erik S.; Schmidt, Anne W.; Sprouse, Jeffrey S.; Wikstroem, Hakan V.; Grol, Cor J. Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5365 - 5374

1026388-93-1

67292-68-6

Literature: Vermeulen, Erik S.; Schmidt, Anne W.; Sprouse, Jeffrey S.; Wikstroem, Hakan V.; Grol, Cor J. Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5365 - 5374

2882-15-7

67292-68-6

Literature: Shaw Journal of the American Chemical Society, 1955 , vol. 77, p. 4319,4320 Journal of the American Chemical Society, 1956 , vol. 78, p. 6419

189884-58-0

67292-68-6

Literature: Vermeulen, Erik S.; Schmidt, Anne W.; Sprouse, Jeffrey S.; Wikstroem, Hakan V.; Grol, Cor J. Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5365 - 5374

Precursor 8
79098-38-7 19501-58-7 28089-03-4 50-00-0
100722-77-8 1076-74-0 1026388-93-1 2882-15-7
DownStream 0

2763779-77-5	2763756-67-6
2763779-82-2	2246856-38-0
2763931-36-6	2411250-51-4
2411195-33-8	2411251-95-9
1027706-58-6	2763894-52-4