30236-31-8
30236-31-8 structure
- Name: l-Sotalol
- Chemical Name: N-{4-[(1R)-1-Hydroxy-2-(isopropylamino)ethyl]phenyl}methanesulfonamide
- CAS Number: 30236-31-8
- Molecular Formula: C12H20N2O3S
- Molecular Weight: 272.364
- Create Date: 2021-09-12 19:59:26
- Modify Date: 2024-04-10 20:25:54
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(-)-Sotalol is a non-selective competitive beta-adrenergic receptor blocker that also shows Class III antiarrhythmic properties.
| Name | N-{4-[(1R)-1-Hydroxy-2-(isopropylamino)ethyl]phenyl}methanesulfonamide |
|---|---|
| Synonyms |
N-{4-[(1R)-1-Hydroxy-2-(isopropylamino)ethyl]phenyl}methanesulfonamide
Methanesulfonamide, N-[4-[(1R)-1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]- N-{4-[(1R)-1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide |
| Description | (-)-Sotalol is a non-selective competitive beta-adrenergic receptor blocker that also shows Class III antiarrhythmic properties. |
|---|---|
| References | 1. Darpo B, Karnad DR, Badilini F, Florian J, Garnett CE, Kothari S, Panicker GK, Sarapa N. Are women more susceptible than men to drug-induced QT prolongation? Concentration-QTc modelling in a phase 1 study with oral rac-sotalol. Br J Clin Pharmacol. 2014 Mar;77(3):522-31. doi: 10.1111/bcp.12201. PubMed PMID: 23819796; PubMed Central PMCID: PMC4371537. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 443.3±55.0 °C at 760 mmHg |
| Molecular Formula | C12H20N2O3S |
| Molecular Weight | 272.364 |
| Flash Point | 221.9±31.5 °C |
| Exact Mass | 272.119476 |
| LogP | 0.32 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.571 |